Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CFTR | P13569 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785242 | 0.80 | POLB (0.60) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL8781797 | 0.79 | POLB (0.59) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL21565076 | 0.79 | POLB (0.73) | RAB9AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29894470 | 0.79 | POLB (0.73) | RAB9AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL28561573 | 0.78 | POLB (0.64) | RAB9AALDH1A1HPGDMEN1MAPT | |
| SCHEMBL9464627 | 0.77 | POLB (0.88) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL28568043 | 0.76 | MAPT (0.64) | RAB9AHPGDMEN1MAPTKMT2A | |
| SCHEMBL29894627 | 0.76 | MAPT (0.64) | RAB9AHPGDMEN1MAPTKMT2A | |
| SCHEMBL13676201 | 0.76 | TRPV1 (0.66) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL24803633 | 0.75 | POLB (0.57) | RAB9AALDH1A1HPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019228299-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | 江苏正大丰海制药有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |