Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | STK17B | O94768 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17196024 | 0.85 | CYP3A4 (0.48) | TDP1CA1CA2STK17BSTK17A | |
| SCHEMBL23660644 | 0.85 | STK17B (0.52) | TDP1CA1CA2STK17BSTK17A | |
| SCHEMBL17987798 | 0.84 | TDP1 (0.51) | TDP1CA1CA2STK17BSTK17A | |
| SCHEMBL2586887 | 0.84 | L3MBTL1 (0.54) | TDP1CA1CA2CYP3A4L3MBTL1 | |
| SCHEMBL30006337 | 0.84 | L3MBTL1 (0.54) | TDP1CA1CA2CYP3A4L3MBTL1 | |
| SCHEMBL17195720 | 0.84 | CA1 (0.48) | TDP1CA1CA2STK17BSTK17A | |
| SCHEMBL14454939 | 0.83 | TDP1 (0.50) | TDP1CA1CA2STK17BSTK17A | |
| SCHEMBL29612932 | 0.83 | CA12 (0.43) | TDP1CA1CA2STK17BSTK17A | |
| SCHEMBL21107306 | 0.83 | CA12 (0.43) | TDP1CA1CA2STK17BSTK17A | |
| SCHEMBL21583947 | 0.81 | CA1 (0.44) | TDP1CA1CA2STK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019228443-A1 | SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2019-12-05 | — | — | WO | disclosed |