Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605676 | 0.93 | IDO1 (0.62) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL2158616 | 0.86 | IDO1 (0.50) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL19263826 | 0.85 | CYP1A2 (0.59) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL5574530 | 0.85 | IGF1R (0.48) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL332100 | 0.79 | GFER (0.42) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL6267935 | 0.78 | FFAR1 (0.54) | IDO1TAAR1HRH3KCNH2FDFT1 | |
| SCHEMBL2494547 | 0.78 | CYP1A2 (0.52) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL5609061 | 0.78 | IDO1 (0.56) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL5610023 | 0.76 | IDO1 (0.54) | IDO1CYP1A2CYP2A6TAAR1HRH3 | |
| SCHEMBL19676926 | 0.76 | CYP1A2 (0.50) | IDO1CYP1A2CYP2A6TAAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9415328-B2 | Modified surfaces | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-08-16 | — | — | US | disclosed |
| US-20140311966-A1 | MODIFIED SURFACES | UNIV ST ANDREWS (GB) | 2014-10-23 | — | — | US | disclosed |
| US-8778454-B2 | Modified surfaces | UNIVERSIT COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2014-07-15 | — | — | US | disclosed |
| US-20110183123-A1 | Modified Surfaces | University Court of the University of St. Andrews College Gate (GB) | 2011-07-28 | — | — | US | disclosed |