Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574530 | 0.94 | IGF1R (0.48) | IDO1CYP1A2CYP2A6TAAR1IGF1R | |
| SCHEMBL5609061 | 0.93 | IDO1 (0.56) | IDO1CYP1A2CYP2A6TAAR1IGF1R | |
| SCHEMBL2158412 | 0.86 | IDO1 (0.54) | IDO1CYP1A2CYP2A6TAAR1IGF1R | |
| SCHEMBL5610023 | 0.86 | IDO1 (0.54) | IDO1CYP1A2CYP2A6TAAR1IGF1R | |
| SCHEMBL12125077 | 0.84 | IDO1 (0.52) | IDO1CYP1A2CYP2A6TAAR1IGF1R | |
| SCHEMBL14367056 | 0.83 | RARB (0.47) | HRH3RARBTSHRHSD17B10 | |
| SCHEMBL19263826 | 0.81 | CYP1A2 (0.59) | IDO1CYP1A2CYP2A6TAAR1IGF1R | |
| SCHEMBL24372592 | 0.80 | FFAR1 (0.50) | IDO1TAAR1FDFT1KCNH2TSHR | |
| SCHEMBL2492800 | 0.80 | RARB (0.58) | CYP1A2CYP2A6TAAR1IGF1RALOX15 | |
| SCHEMBL5605676 | 0.79 | IDO1 (0.62) | IDO1CYP1A2CYP2A6TAAR1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9415328-B2 | Modified surfaces | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-08-16 | — | — | US | disclosed |
| US-20140311966-A1 | MODIFIED SURFACES | UNIV ST ANDREWS (GB) | 2014-10-23 | — | — | US | disclosed |
| US-8778454-B2 | Modified surfaces | UNIVERSIT COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2014-07-15 | — | — | US | disclosed |
| US-20110183123-A1 | Modified Surfaces | University Court of the University of St. Andrews College Gate (GB) | 2011-07-28 | — | — | US | disclosed |