Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584477 | 0.94 | ALDH1A1 (0.41) | LMNARAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL1610274 | 0.89 | ALDH1A1 (0.42) | LMNARAB9AKDM4EMAPTTHRB | |
| SCHEMBL2683873 | 0.86 | ALDH1A1 (0.39) | LMNARAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL1609507 | 0.86 | MAPT (0.44) | LMNARAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL22181356 | 0.85 | MAPT (0.42) | LMNARAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL21584372 | 0.84 | POLB (0.36) | LMNARAB9AKDM4EMAPTHPGD | |
| SCHEMBL1610795 | 0.82 | ALDH1A1 (0.42) | LMNARAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL1609593 | 0.82 | ALDH1A1 (0.42) | LMNARAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13076207 | 0.82 | KDM4E (0.40) | LMNARAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL1610835 | 0.81 | ALDH1A1 (0.45) | LMNARAB9AKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019227771-A1 | SUBSTITUTED PYRIMIDINE-4-FORMIC ACID DERIVATIVE, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |