Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DHPS | P49366 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584385 | 0.93 | MAPT (0.44) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL21584431 | 0.89 | CASP3 (0.40) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL21584335 | 0.88 | MAPT (0.40) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL21584437 | 0.87 | MAPT (0.38) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL21584480 | 0.87 | MAPT (0.46) | MAPTALDH1A1KDM4EGAAADORA2A | |
| SCHEMBL679235 | 0.87 | GRM6 (0.37) | MAPTALDH1A1KDM4EDHPSLMNA | |
| SCHEMBL21584432 | 0.87 | TDP1 (0.46) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL29443551 | 0.87 | TDP1 (0.46) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL21584500 | 0.86 | HTT (0.37) | MAPTALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL21584435 | 0.86 | MAPT (0.37) | MAPTALDH1A1KDM4EKMT2ADHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019227771-A1 | SUBSTITUTED PYRIMIDINE-4-FORMIC ACID DERIVATIVE, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |