SCHEMBL21584430

SCHEMBL21584430

O=C(O)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(OC(=O)c4cc(O)c(O)c(O)c4)c3)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 1.00
POLA1 P09884 1/20 1.00
ANTXR2 P58335 1/20 1.00
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA6 P23280 3/20 0.65
KDM4E B2RXH2 2/20 0.65
LMNA P02545 2/20 0.65
FUT7 Q11130 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
CA12 O43570 2/20 0.65
CA3 P07451 2/20 0.65
CA4 P22748 2/20 0.65
CA5A P35218 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
CA5B Q9Y2D0 2/20 0.65
MAPK1 P28482 2/20 0.65
SELL P14151 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Digallic Acid SCHEMBL39415 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL29620339 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL30257247 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL30307875 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
Digallic Acid SCHEMBL29836990 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL21584439 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL23750585 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL21584579 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL21584424 1.00 POLB (1.00) POLBPOLA1ANTXR2CA1CA2
SCHEMBL30307880 0.90 POLB (0.81) POLBPOLA1ANTXR2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11779561-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-10 US disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
WO-2021155864-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) 2021-08-12 WO disclosed
US-20210214385-A1 INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2021-07-15 US disclosed
US-10927138-B2 Inhibitors of D-amino acid oxidase (DAAO) and uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2021-02-23 US disclosed
WO-2019228408-A1 POTENT INHIBITORS OF D-AMINO ACID OXIDASE (DAAO) AND USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) 2019-12-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214385-A1 INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF DAO, DDO, DDC POLB 1656/4885POLA1 1865/4885ANTXR2 3140/4885
US-10927138-B2 Inhibitors of D-amino acid oxidase (DAAO) and uses thereof DAO, DDO, DDC POLB 1988/4885POLA1 2104/4885ANTXR2 3178/4885
US-11779561-B2 Compounds and pharmaceutical uses thereof ACE, ACE2, FURIN POLB 2146/4885POLA1 3124/4885ANTXR2 4628/4885
US-11793823-B2 Compounds and pharmaceutical uses thereof HRH4, OR10J3, CYP3A5 POLB 4471/4885POLA1 4203/4885ANTXR2 1348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.