Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25738952 | 0.82 | GRIN1 (0.40) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL13460109 | 0.78 | GRIN1 (0.40) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL26456980 | 0.77 | GRIN1 (0.42) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL24782527 | 0.74 | — | — | |
| SCHEMBL25476574 | 0.73 | CHRM2 (0.41) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL27390148 | 0.72 | LTA4H (0.33) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL10186820 | 0.70 | GRIN1 (0.38) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL10186798 | 0.70 | GRIN1 (0.38) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL10186825 | 0.70 | GRIN1 (0.38) | GRIN1GRIN2ACHRM2CHRM3LTA4H | |
| SCHEMBL16190002 | 0.70 | GRIN1 (0.42) | GRIN1GRIN2ACHRM2CHRM3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019228252-A1 | HIGHLY ACTIVE CSF1R INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |