SCHEMBL21585350

SCHEMBL21585350

CC1(C)c2ccccc2Oc2cc(N)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.47
KDM4E B2RXH2 5/20 0.47
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 4/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
LMNA P02545 1/20 0.44
FTO Q9C0B1 3/20 0.39
PDK2 Q15119 2/20 0.37
HPGD P15428 2/20 0.34
HTR2A P28223 1/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12777465 0.89 SMN1; SMN2 (0.47) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL29878482 0.89 SMN1; SMN2 (0.47) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL14327440 0.87 SMN1; SMN2 (0.38) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL47009 0.82 ALOX5 (0.44) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29360424 0.82 ALOX5 (0.44) MAPTMEN1KMT2ASMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL10624875 0.80 ALOX5 (0.42) MAPTMEN1KMT2ASMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL10624869 0.80 ALOX5 (0.42) MAPTMEN1KMT2ASMN1; SMN2NPC1
Phosphine SCHEMBL17530281 0.80 ALOX5 (0.42) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL31243239 0.80 ALOX5 (0.42) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL26156926 0.80 PDK2 (0.41) MAPTKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019228430-A1 KETONE-CONTAINING COMPOUND AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE 江苏三月光电科技有限公司 (CN) 2019-12-05 WO disclosed
CN-107868049-A Organic compound and organic electroluminescence device using the fluorenes of 9,9 ' spiral shell two as core 江苏三月光电科技有限公司 2018-04-03 CN disclosed