Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496795 | 0.90 | TDP1 (0.66) | TDP1AKR1B1SLC22A12THRATHRB | |
| SCHEMBL21585557 | 0.87 | AKR1B1 (0.63) | TDP1AKR1B1SLC22A12THRATHRB | |
| SCHEMBL30504155 | 0.83 | MAPK1 (0.45) | TDP1AKR1B1CYP1A2 | |
| SCHEMBL3045619 | 0.83 | MAPK1 (0.45) | TDP1AKR1B1CYP1A2 | |
| SCHEMBL21585553 | 0.82 | TDP1 (0.59) | TDP1AKR1B1POLBCYP1A2KMT2A | |
| SCHEMBL6948017 | 0.82 | TDP1 (0.55) | TDP1AKR1B1SLC22A12THRATHRB | |
| SCHEMBL19019569 | 0.82 | TDP1 (0.55) | TDP1AKR1B1SLC22A12THRATHRB | |
| SCHEMBL21585560 | 0.80 | TDP1 (0.66) | TDP1AKR1B1THRATHRBKMT2A | |
| SCHEMBL14564415 | 0.79 | TDP1 (0.64) | TDP1AKR1B1SLC22A12CYP1A2KMT2A | |
| SCHEMBL31618299 | 0.79 | TDP1 (0.64) | TDP1AKR1B1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970921-B | High-water-reduction low-sensitivity polycarboxylate superplasticizer and preparation method thereof | 科之杰新材料集团有限公司 | 2020-07-03 | — | — | CN | claimed |
| WO-2019233215-A1 | HIGH WATER-REDUCING AND LOW SENSITIVITY POLYCARBOXYLATE SUPERPLASTICIZER AND PREPARATION METHOD THEREFOR | 科之杰新材料集团有限公司 (CN) | 2019-12-12 | — | — | WO | claimed |
| CN-109970921-B | High-water-reduction low-sensitivity polycarboxylate superplasticizer and preparation method thereof | 科之杰新材料集团有限公司 | 2020-07-03 | — | — | CN | disclosed |
| WO-2019233215-A1 | HIGH WATER-REDUCING AND LOW SENSITIVITY POLYCARBOXYLATE SUPERPLASTICIZER AND PREPARATION METHOD THEREFOR | 科之杰新材料集团有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |