Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20897567 | 0.82 | MRGPRX4 (0.64) | MRGPRX4RXRARXRBRXRGNR4A2 | |
| SCHEMBL20897512 | 0.81 | MRGPRX4 (0.63) | MAOBMAOAMRGPRX4RXRARXRB | |
| SCHEMBL21585879 | 0.80 | BRD4 (0.48) | — | |
| SCHEMBL30359958 | 0.80 | BRD4 (0.48) | — | |
| SCHEMBL21585883 | 0.79 | FNTA (0.53) | MAOBMAOAMRGPRX4NPC1ALDH1A1 | |
| SCHEMBL8694329 | 0.78 | MAOB (1.00) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL29029641 | 0.78 | KMT2A (0.47) | MAOBMAOANPC1ALDH1A1RAB9A | |
| SCHEMBL6211864 | 0.78 | MRGPRX4 (0.62) | MRGPRX4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL366522 | 0.77 | MRGPRX4 (0.56) | MAOBMAOAMRGPRX4NPC1ALDH1A1 | |
| SCHEMBL8143434 | 0.74 | HPGD (0.54) | MRGPRX4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802550-B1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INST NAT SANTE RECH MED (FR) | 2023-12-27 | — | — | EP | disclosed |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-09-26 | — | — | US | disclosed |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (FR) | 2022-08-25 | — | — | US | disclosed |
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2022-06-07 | — | — | US | disclosed |
| US-20210253604-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2021-08-19 | — | — | US | disclosed |
| EP-3802550-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019234075-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK5 | MAOB 882/4885MAOA 828/4885MRGPRX4 1280/4885 |
| US-20210253604-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | KLKB1, KLK1, KLK2 | MAOB 1018/4885MAOA 769/4885MRGPRX4 1047/4885 |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | KLKB1, KLK1, KLK2 | MAOB 1026/4885MAOA 858/4885MRGPRX4 1055/4885 |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK2 | MAOB 844/4885MAOA 843/4885MRGPRX4 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.