Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.53 |
| ▸ | FNTB | P49356 | 2/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029641 | 0.81 | KMT2A (0.47) | FNTAFNTBPGGT1BMAOAMAOB | |
| SCHEMBL27863823 | 0.80 | TTR (0.57) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL9656856 | 0.80 | MAOA (0.48) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL7984102 | 0.80 | AR (0.56) | FNTAFNTBPGGT1BARSLC22A12 | |
| SCHEMBL21585885 | 0.79 | MAOB (0.65) | MAOAMAOBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2775115 | 0.79 | MAPT (0.63) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL9656929 | 0.76 | KMT2A (0.52) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL11176242 | 0.74 | MRGPRX4 (0.47) | ARMAPTSMN1; SMN2MRGPRX4LMNA | |
| SCHEMBL7293099 | 0.74 | ALDH1A1 (0.56) | ARMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL23830071 | 0.74 | AR (0.53) | FNTAFNTBPGGT1BARSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802550-B1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INST NAT SANTE RECH MED (FR) | 2023-12-27 | — | — | EP | disclosed |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-09-26 | — | — | US | disclosed |
| CN-112236433-B | Novel compounds | 国家医疗保健研究所 | 2023-04-04 | — | — | CN | disclosed |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (FR) | 2022-08-25 | — | — | US | disclosed |
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2022-06-07 | — | — | US | disclosed |
| US-20210253604-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2021-08-19 | — | — | US | disclosed |
| EP-3802550-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2021-04-14 | — | — | EP | disclosed |
| CN-112236433-A | Novel compounds | 国家医疗保健研究所 | 2021-01-15 | — | — | CN | disclosed |
| WO-2019234075-A1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK5 | FNTA 4679/4885FNTB 4378/4885PGGT1B 1757/4885 |
| US-20210253604-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | KLKB1, KLK1, KLK2 | FNTA 4733/4885FNTB 4461/4885PGGT1B 1815/4885 |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | KLKB1, KLK1, KLK2 | FNTA 4733/4885FNTB 4462/4885PGGT1B 1855/4885 |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK2 | FNTA 4701/4885FNTB 4388/4885PGGT1B 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.