Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 20/20 | 0.86 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.86 |
| ▸ | HDAC2 | Q92769 | 19/20 | 0.86 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.86 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.86 |
| ▸ | NCOR2 | Q9Y618 | 9/20 | 0.86 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.86 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.86 |
| ▸ | UBA1 | P22314 | 1/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19022542 | 1.00 | HDAC3 (0.86) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL17305526 | 1.00 | HDAC3 (0.86) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL22810153 | 1.00 | HDAC3 (0.86) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL19047320 | 1.00 | HDAC3 (0.86) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL12611184 | 0.93 | HDAC3 (0.88) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL12651856 | 0.93 | HDAC3 (0.88) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL10315069 | 0.93 | HDAC3 (0.86) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| Largazole Thiol SCHEMBL15195503 | 0.93 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL12610998 | 0.93 | HDAC3 (0.86) | HDAC3HDAC1HDAC2HDAC6HDAC8 | |
| Largazole Thiol SCHEMBL7994520 | 0.93 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578179-B1 | PROCESS FOR THE PREPARATION OF CYCLIC DEPSIPEPTIDES | ONKURE INC (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3578179-A1 | PROCESS FOR THE PREPARATION OF CYCLIC DEPSIPEPTIDES | Onkure, Inc. (US) | 2019-12-11 | — | — | EP | disclosed |