Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069706 | 1.00 | TSHR (0.61) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL2352256 | 1.00 | TSHR (0.61) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL6449183 | 0.98 | TSHR (0.58) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL27377604 | 0.91 | TSHR (0.54) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL9788553 | 0.90 | TSHR (0.77) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL930891 | 0.90 | TSHR (0.77) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL15130313 | 0.88 | TSHR (0.74) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL6274691 | 0.86 | TSHR (0.53) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL10948447 | 0.85 | TSHR (0.61) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL9718041 | 0.84 | TSHR (0.48) | TSHRHPGDHCAR2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413692-B1 | COMPOSITIONS OF VOLATILE ORGANIC COMPOUNDS AND METHODS OF USE THEREOF | SYNTHETIC GENOMICS INC (US) | 2018-08-29 | — | — | EP | disclosed |
| US-20150173356-A1 | COMPOSITIONS OF VOLATILE ORGANIC COMPOUNDS AND METHODS OF USE THEREOF | SYNTHETIC GENOMICS, INC. | 2015-06-25 | — | — | US | disclosed |
| US-8968798-B2 | Compositions of volatile organic compounds and methods of use thereof | SYNTHETIC GENOMICS, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130224315-A1 | Compositions of Volatile Organic Compounds and Methods of User Thereof | SYNTHETIC GENOMICS, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-8425946-B2 | Compositions of volatile organic compounds and methods of use thereof | SYNTHETIC GENOMICS, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20110182862-A1 | ENDOPHYTIC FUNGUS AND USES THEREFOR | SYNTHETIC GENOMICS, INC. | 2011-07-28 | — | — | US | disclosed |
| US-20100255124-A1 | COMPOSITIONS OF VOLATILE ORGANIC COMPOUNDS AND METHODS OF USE THEREOF | SYNTHETIC GENOMICS, INC. (US) | 2010-10-07 | — | — | US | disclosed |