SCHEMBL2352256

SCHEMBL2352256

C=CCOC(=O)C(=O)OCCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.61
NAAA Q02083 1/20 0.50
HPGD P15428 1/20 0.48
HCAR2 Q8TDS4 2/20 0.47
RAD52 P43351 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
EPHX1 P07099 1/20 0.47
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 1/20 0.44
ATM Q13315 1/20 0.42
FAAH O00519 1/20 0.42
LMNA P02545 1/20 0.42
ACHE P22303 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31069706 1.00 TSHR (0.61) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL2158706 1.00 TSHR (0.61) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL6449183 0.98 TSHR (0.58) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL27377604 0.91 TSHR (0.54) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL9788553 0.90 TSHR (0.77) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL930891 0.90 TSHR (0.77) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL15130313 0.88 TSHR (0.74) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL6274691 0.86 TSHR (0.53) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL10948447 0.85 TSHR (0.61) TSHRNAAAHPGDHCAR2RAD52
SCHEMBL9718041 0.84 TSHR (0.48) TSHRHPGDHCAR2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735004-B2 Overcharge inhibitor, and nonaqueous electrolyte solution and secondary battery using the same HITACHI, LTD. (JP) 2014-05-27 US disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
EP-2355228-A1 Overcharge inhibitor, and nonaqueous electrolyte solution and secondary battery using the same Hitachi Ltd. (JP) 2011-08-10 EP disclosed
US-20110189550-A1 OVERCHARGE INHIBITOR, AND NONAQUEOUS ELECTROLYTE SOLUTION AND SECONDARY BATTERY USING THE SAME HITACHI, LTD. 2011-08-04 US disclosed
US-7803298-B2 Molding material, molded part, and method for manufacturing them SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2010-09-28 US disclosed
US-20090085260-A1 BIODEGRADABLE MATERIAL AND PROCESS FOR PRODUCING THE SAME JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2009-04-02 US disclosed
US-20090030160-A1 Polylactic Acid Complex and Production Method Thereof SUMITOMO ELECTRIC FINE POLYMER INC. (JP) 2009-01-29 US disclosed
US-20080213209-A1 Process for Producing Cross-Linked Material of Polylactic Acid and Cross-Linked Material of Polylactic Acid SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2008-09-04 US disclosed
US-20080036119-A1 Molding material, molded part, and method for manufacturing them SUMITOMO ELECTRIC FINE POLYMER, INC. 2008-02-14 US disclosed
US-20060160984-A1 Biodegradable material and process for producing the same JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2006-07-20 US disclosed
US-20050242466-A1 Process for producing transparent material made of polylactic acid and transparent material made of polylactic acid SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2005-11-03 US disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085260-A1 BIODEGRADABLE MATERIAL AND PROCESS FOR PRODUCING THE SAME TST, PCMT1, XRCC6 TSHR 4354/4885NAAA 276/4885HPGD 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.