Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676589 | 0.83 | IDO1 (0.52) | IDO1AGXTTRPA1MAOBAPP | |
| SCHEMBL14443338 | 0.81 | AGXT (0.50) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL19598855 | 0.80 | IDO1 (0.45) | IDO1AGXTTRPA1MAOBAPP | |
| SCHEMBL5728580 | 0.80 | IDO1 (0.50) | IDO1AGXTTRPA1MAOBAPP | |
| SCHEMBL1927583 | 0.80 | IDO1 (0.50) | IDO1AGXTTRPA1MAOBAPP | |
| SCHEMBL7284728 | 0.79 | IDO1 (0.48) | IDO1AGXTTRPA1MAOBAPP | |
| SCHEMBL2308449 | 0.79 | IDO1 (0.48) | IDO1AGXTTRPA1MAOBAPP | |
| SCHEMBL8781581 | 0.79 | IDO1 (0.54) | IDO1AGXTTRPA1MAOBAPP | |
| Hydrochloric Acid SCHEMBL1927188 | 0.79 | IDO1 (0.52) | IDO1AGXTTRPA1MAOBAPP | |
| SCHEMBL20463639 | 0.78 | RCE1 (0.49) | IDO1AGXTTRPA1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578562-A1 | L-VALINATE AMIDE BENZOXABOROLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES | Anacor Pharmaceuticals, Inc (US) | 2019-12-11 | — | — | EP | disclosed |