Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 9/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23634056 | 0.82 | IDO1 (0.47) | IDO1AGXTMAOBLOXL2TRPA1 | |
| SCHEMBL17227561 | 0.82 | LOXL2 (0.43) | IDO1MAOBLOXL2APPCHRNB2 | |
| SCHEMBL18579549 | 0.81 | CHRNA4 (0.56) | IDO1AGXTMAOBTAAR1CA1 | |
| SCHEMBL17227254 | 0.81 | CHRNA4 (0.56) | IDO1AGXTMAOBTAAR1CA1 | |
| SCHEMBL7864015 | 0.80 | IDO1 (0.46) | IDO1AGXTMAOBLOXL2TAAR1 | |
| SCHEMBL8781581 | 0.80 | IDO1 (0.54) | IDO1AGXTMAOBLOXL2TAAR1 | |
| SCHEMBL21587147 | 0.80 | IDO1 (0.48) | IDO1AGXTMAOBLOXL2TAAR1 | |
| SCHEMBL18579815 | 0.80 | IDO1 (0.46) | IDO1AGXTMAOBLOXL2TAAR1 | |
| SCHEMBL18580195 | 0.80 | IDO1 (0.46) | IDO1AGXTMAOBLOXL2TAAR1 | |
| SCHEMBL6676589 | 0.79 | IDO1 (0.52) | IDO1AGXTMAOBLOXL2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |