⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33843 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7115195 | 0.77 | PI4KA (0.38) | — | |
| SCHEMBL15897513 | 0.75 | — | — | |
| SCHEMBL18283698 | 0.75 | — | — | |
| SCHEMBL20843901 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL22774499 | 0.73 | — | — | |
| SCHEMBL17619420 | 0.72 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL13093485 | 0.72 | — | — | |
| SCHEMBL2067300 | 0.72 | — | — | |
| SCHEMBL21719474 | 0.71 | CYP11B2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250376473-A1 | PRMTS INHIBITOR AND USE THEREOF | CYTOSINLAB THERAPEUTICS CO LTD (CN) | 2025-12-11 | — | — | US | disclosed |
| EP-4549440-A1 | CLASS OF PRMT5 INHIBITORS AND USE THEREOF | Cytosinlab Therapeutics Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| EP-4549442-A1 | PRMT5 INHIBITORS AND USE THEREOF | Cytosinlab Therapeutics Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| CN-119562954-A | PRMT5 inhibitor and application thereof | 上海赛岚生物科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119487041-A | PRMT5 inhibitor and application thereof | 上海赛岚生物科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20240376126-A1 | PRMT5 INHIBITOR AND THE USE THEREOF | CYTOSINLAB THERAPEUTICS CO., LTD. (CN) | 2024-11-14 | — | — | US | disclosed |
| WO-2024002376-A1 | PRMT5 INHIBITORS AND USE THEREOF | 上海赛岚生物科技有限公司 | 2024-01-04 | — | — | WO | disclosed |
| WO-2024002377-A1 | CLASS OF PRMT5 INHIBITORS AND USE THEREOF | 上海赛岚生物科技有限公司 | 2024-01-04 | — | — | WO | disclosed |
| US-11466013-B2 | ERK inhibitor and use thereof | BETTA PHARMACEUTICALS CO., LTD (CN) | 2022-10-11 | — | — | US | disclosed |
| EP-3805217-A1 | ERK INHIBITOR AND USE THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019233457-A1 | ERK INHIBITOR AND USE THEREOF | 贝达药业股份有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |
| WO-2019233456-A1 | ERK INHIBITOR AND USE THEREOF | 贝达药业股份有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |