Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 18/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 18/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 18/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15529338 | 0.92 | OPRL1 (0.42) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL28695591 | 0.78 | OPRL1 (0.46) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL28444682 | 0.72 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL30062630 | 0.71 | OPRL1 (0.42) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL23232266 | 0.71 | OPRL1 (0.42) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL16766351 | 0.71 | — | — | |
| SCHEMBL16767609 | 0.71 | PDK2 (0.35) | — | |
| SCHEMBL16767624 | 0.71 | OPRL1 (0.35) | OPRL1OPRM1OPRD1 | |
| SCHEMBL28707532 | 0.70 | OPRL1 (0.38) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL30408176 | 0.70 | OPRL1 (0.50) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019233456-A1 | ERK INHIBITOR AND USE THEREOF | 贝达药业股份有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |