Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2A | O00443 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589401 | 0.86 | PIK3C2A (0.67) | PIK3C2AALDH1A1POLBPIK3C2B | |
| SCHEMBL21589376 | 0.82 | PIK3C2A (0.61) | PIK3C2AALDH1A1POLBCA12CA2 | |
| SCHEMBL21586306 | 0.76 | PIK3C2A (1.00) | PIK3C2AMAPTPIK3C2B | |
| SCHEMBL9671550 | 0.74 | PDE7A (0.65) | ALDH1A1CA12CA2CA9CA1 | |
| SCHEMBL21589406 | 0.74 | PIK3C2A (0.65) | PIK3C2AALDH1A1MAPTPIK3C2BALDH1A2 | |
| SCHEMBL5921047 | 0.73 | CASR (0.74) | MEN1KMT2A | |
| SCHEMBL21589398 | 0.72 | PIK3C2A (0.65) | PIK3C2APIK3C2B | |
| SCHEMBL6512906 | 0.72 | PDE4A (0.86) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL30003002 | 0.70 | PIK3C2A (0.74) | PIK3C2APIK3C2B | |
| SCHEMBL21586276 | 0.70 | PIK3C2A (0.81) | PIK3C2AALDH1A1POLBMAPTPIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019234237-A1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2019-12-12 | — | — | WO | disclosed |