Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589670 | 0.86 | DRD2 (0.31) | ELANE | |
| SCHEMBL21589621 | 0.86 | NR1H4 (0.33) | ELANE | |
| SCHEMBL24940647 | 0.80 | — | — | |
| SCHEMBL30912778 | 0.78 | ELANE (0.32) | ELANEKDM4EPKM | |
| SCHEMBL21585962 | 0.78 | ELANE (0.32) | ELANEKDM4EPKM | |
| SCHEMBL8333225 | 0.78 | ELANE (0.31) | ELANEKDM4EPKM | |
| SCHEMBL8330763 | 0.78 | ELANE (0.31) | ELANEKDM4EPKM | |
| SCHEMBL21589493 | 0.78 | NR1H4 (0.32) | ELANEKDM4EPKM | |
| SCHEMBL24940626 | 0.73 | NR1H4 (0.35) | — | |
| SCHEMBL19848461 | 0.72 | ELANE (0.33) | ELANEKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802504-B1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2023-01-18 | — | — | EP | disclosed |
| WO-2019234077-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2019-12-12 | — | — | WO | disclosed |