⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22116319 | 0.92 | — | — | |
| SCHEMBL3945690 | 0.84 | — | — | |
| SCHEMBL1829070 | 0.83 | — | — | |
| SCHEMBL380749 | 0.81 | — | — | |
| SCHEMBL1830501 | 0.80 | — | — | |
| SCHEMBL8309792 | 0.74 | HTR2C (0.30) | — | |
| SCHEMBL16012878 | 0.74 | HTR2C (0.30) | — | |
| SCHEMBL17048746 | 0.72 | — | — | |
| SCHEMBL10979142 | 0.72 | — | — | |
| SCHEMBL3702501 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402911-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2022-12-22 | — | — | US | disclosed |
| US-20220251075-A1 | Cycloalkyl and Heterocycloalkyl Benzisoxazole Sulfonamide Derivatives | PFIZER INC. | 2022-08-11 | — | — | US | disclosed |
| EP-3806853-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | Galapagos NV (BE) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020254989-A1 | CYCLOALKYL AND HETEROCYCLOALKYL BENZISOXAZOLE SULFONAMIDE DERIVATIVES | PFIZER INC. (US) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020239660-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2020-12-03 | — | — | WO | disclosed |
| WO-2019238424-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2019-12-19 | — | — | WO | disclosed |