SCHEMBL8309792

SCHEMBL8309792

[CH]1CCOC12CCCNCCC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2655503 0.86 HTR2C (0.32) HTR2C
SCHEMBL1829070 0.84
SCHEMBL380749 0.81
SCHEMBL16012878 0.78 HTR2C (0.30) HTR2C
SCHEMBL15210508 0.74
SCHEMBL21591045 0.74
SCHEMBL22116319 0.72
SCHEMBL14715309 0.72
SCHEMBL459255 0.71
SCHEMBL3945690 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912560-A1 INDOLE DERIVATIVES FOR THE TREATMENT OF OSTEOPOROSIS Smithkline Beecham S.p.A. (IT) 1999-05-06 EP disclosed
WO-1998001445-A1 INDOLE DERIVATIVES FOR THE TREATMENT OF OSTEOPOROSIS SMITHKLINE BEECHAM S.P.A. (IT) 1998-01-15 WO disclosed