Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211926 | 0.83 | VNN1 (0.33) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL21195994 | 0.83 | VNN1 (0.33) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL21195953 | 0.83 | VNN1 (0.33) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL23245626 | 0.81 | KDM4E (0.34) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL12490749 | 0.80 | NPC1 (0.34) | KDM4EMEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL21196163 | 0.80 | NPC1 (0.34) | KDM4EMEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL18669380 | 0.80 | NPC1 (0.34) | KDM4EMEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL21585780 | 0.79 | — | — | |
| SCHEMBL30327233 | 0.79 | SMN1; SMN2 (0.43) | CNR2KDM4EMEN1USP2CYP3A4 | |
| SCHEMBL619913 | 0.77 | VNN1 (0.36) | KDM4EMEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266258-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF IRAK-4 | ARVINAS OPERATIONS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| EP-3806853-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | Galapagos NV (BE) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238424-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2019-12-19 | — | — | WO | disclosed |
| CN-110256418-A | The benzamide that 1,3- thiazol-2-yl replaces | 拜耳公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-107207507-A | 1, 3-thiazol-2-yl substituted benzamides | 拜耳公司 | 2017-09-26 | — | — | CN | disclosed |