SCHEMBL2159162

SCHEMBL2159162

O=C(O)C1CC2CC1C1OC21.[AlH3]

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.34
PKM P14618 1/20 0.32
TSHR P16473 1/20 0.31
GABRR2 P28476 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1001420 0.98 GABRR1 (0.36) GABRR1PKMTSHRGABRR2
SCHEMBL31425776 0.96 GABRR1 (0.34) GABRR1PKMTSHRGABRR2
Di(Hydroxyethyl)Ether SCHEMBL5718548 0.83 TSHR (0.31) TSHR
SCHEMBL2159493 0.78
SCHEMBL2159647 0.78
SCHEMBL1919854 0.78
SCHEMBL2158543 0.78
SCHEMBL10159530 0.75 CHRNB2 (0.35) TSHR
SCHEMBL25391396 0.74
SCHEMBL16898793 0.73 CHRNB2 (0.33) GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802346-B2 Metal compositions and methods of making same PRYOG, LLC (US) 2014-08-12 US disclosed
US-8709705-B2 Metal-containing compositions and method of making same PRYOG, LLC (US) 2014-04-29 US disclosed
US-20120315451-A1 Metal-Containing Compositions and Method of Making Same PRYOG LLC 2012-12-13 US disclosed
US-20110184139-A1 METAL COMPOSITIONS AND METHODS OF MAKING SAME PRYOG, LLC 2011-07-28 US disclosed