SCHEMBL21592231

SCHEMBL21592231

Fc1cc(CNCCCn2ccnc2)ccn1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.47
▸ VEGFA P15692 1/20 0.45
▸ EGLN1 Q9GZT9 1/20 0.45
▸ QPCT Q16769 5/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ DRD4 P21917 1/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ TSHR P16473 1/20 0.44
▸ AKT1 P31749 1/20 0.43
▸ AKT2 P31751 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ SOD1 P00441 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14416010 0.82 SMN1; SMN2 (0.56) CYP19A1VEGFAEGLN1QPCTSMN1; SMN2
SCHEMBL14416007 0.82 CYP11B1 (0.60) CYP19A1VEGFAEGLN1QPCTSMN1; SMN2
SCHEMBL3181153 0.82 SMN1; SMN2 (0.57) CYP19A1VEGFAEGLN1QPCTSMN1; SMN2
SCHEMBL21591530 0.81 QPCT (0.51) CYP19A1QPCTDRD4MEN1KMT2A
SCHEMBL14416009 0.81 CYP19A1 (0.67) CYP19A1QPCTSMN1; SMN2POLBMAPK1
SCHEMBL2475754 0.78 QPCT (0.67) CYP19A1VEGFAEGLN1QPCTSMN1; SMN2
SCHEMBL8444490 0.78 ALOX15 (0.60) VEGFAEGLN1QPCTALDH1A1
SCHEMBL14416012 0.77 VEGFA (0.55) VEGFAEGLN1QPCTSMN1; SMN2MEN1
SCHEMBL14492302 0.77 CYP11B1 (0.60) VEGFAEGLN1QPCTSMN1; SMN2DRD4
SCHEMBL17572351 0.77 CYP11B1 (0.60) VEGFAEGLN1QPCTSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162863-B2 Modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2024-12-10 — — US disclosed
US-20220402898-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-12-22 — — US disclosed
US-20220402898-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-12-22 — — US disclosed
WO-2019238786-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2019-12-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162863-B2 Modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS CYP19A1 589/4885VEGFA 3195/4885EGLN1 3370/4885
US-20220402898-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS CYP19A1 589/4885VEGFA 3195/4885EGLN1 3370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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