Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.52 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277594 | 0.84 | HTT (0.56) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL2942342 | 0.82 | HTT (0.59) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL2238188 | 0.82 | HTT (0.59) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL10590760 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL15845537 | 0.80 | KDM4E (0.54) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL11451860 | 0.79 | SLC18A2 (0.52) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL14839522 | 0.79 | AOC3 (0.54) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL7604631 | 0.79 | HTT (0.56) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL24827599 | 0.78 | HTT (0.50) | SMN1; SMN2HTTTAAR1CALM1F2RL1 | |
| SCHEMBL10928948 | 0.78 | HTT (0.50) | SMN1; SMN2HTTTAAR1CALM1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238067-A1 | PYRROLO [2, 3-B] PYRIDINES OR PYRROLO [2, 3-B] PYRAZINES AS HPK1 INHIBITOR AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2019-12-19 | — | — | WO | disclosed |