Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942342 | 0.85 | HTT (0.59) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL2238188 | 0.85 | HTT (0.59) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL7774968 | 0.84 | HTT (0.51) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL7277594 | 0.82 | HTT (0.56) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL29657236 | 0.81 | HTT (0.59) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL28851988 | 0.81 | HTT (0.59) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL879606 | 0.80 | HTT (0.62) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL24827599 | 0.80 | HTT (0.50) | HTTSMN1; SMN2CALM1TAAR1MEN1 | |
| SCHEMBL5477927 | 0.80 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL21592910 | 0.79 | SMN1; SMN2 (0.53) | HTTSMN1; SMN2CALM1TAAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799819-B1 | 1-Dimethylaminomethyl 2-phenyl cycloalk-2-ene derivatives with analgesic activity | GRUENENTHAL GMBH (DE) | 2002-09-11 | — | — | EP | disclosed |