⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289796 | 0.80 | — | — | |
| SCHEMBL294437 | 0.77 | — | — | |
| SCHEMBL29272681 | 0.74 | TDP1 (0.48) | — | |
| SCHEMBL1718922 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL27292244 | 0.73 | — | — | |
| SCHEMBL10416322 | 0.71 | — | — | |
| SCHEMBL1289842 | 0.71 | — | — | |
| SCHEMBL6365087 | 0.71 | — | — | |
| SCHEMBL27538444 | 0.71 | SLC22A6 (0.45) | — | |
| SCHEMBL9157043 | 0.71 | FOLH1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985771-B2 | Skin disorders; aging resistance | MONSANTO TECHNOLOGY LLC (US) | 2011-07-26 | — | — | US | disclosed |
| EP-1660080-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20060089355-A1 | Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides | ELAN PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | disclosed |
| EP-1478634-A4 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS INC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005016340-A1 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-1478634-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040029812-A1 | Furanone derivatives | MONSANTO TECHNOLOGY LLC | 2004-02-12 | — | — | US | disclosed |
| US-6667330-B2 | Cytoprotective; neuroinflammation and neurodegenerative disorders; oxidative stress related conditions | GALILEO PHARMACEUTICALS, INC. | 2003-12-23 | — | — | US | disclosed |
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |
| US-20030176361-A1 | Furanone derivatives | MONSANTO TECHNOLOGY LLC | 2003-09-18 | — | — | US | disclosed |
| WO-2003064403-A1 | FURANONE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| US-5641778-A | EXHIBIT RENIN-INHIBITING PROPERTIES AND CAN BE USED AS ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0716077-A1 | Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |