Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.71 |
| ▸ | MMP2 | P08253 | 13/20 | 0.71 |
| ▸ | MMP9 | P14780 | 13/20 | 0.71 |
| ▸ | EGFR | P00533 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-(2-Fluorophenyl)Cinnamamide SCHEMBL1967609 | 0.83 | MMP1 (1.00) | MMP1MMP2MMP9EGFRALDH1A1 | |
| N-(2-Fluorophenyl)Cinnamamide SCHEMBL1967607 | 0.83 | MMP1 (1.00) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL705904 | 0.83 | MMP1 (0.80) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL705905 | 0.83 | MMP1 (0.80) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL11576171 | 0.81 | MMP1 (0.71) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL11575343 | 0.81 | MMP1 (0.71) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL2821162 | 0.80 | MMP1 (0.76) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL3180639 | 0.80 | MMP1 (0.76) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL2819695 | 0.80 | MMP1 (0.76) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL30159590 | 0.80 | MMP1 (0.76) | MMP1MMP2MMP9EGFRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210207175-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-07-08 | — | — | US | disclosed |
| EP-3825409-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2021-05-26 | — | — | EP | disclosed |
| WO-2019238091-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | 中国科学院上海有机化学研究所 | 2019-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210207175-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | TET2, ZFX, ZFR | MMP1 4552/4885MMP2 3182/4885MMP9 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.