Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP4 | P49662 | 1/20 | 0.49 |
| ▸ | CASP5 | P51878 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.49 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577908 | 0.87 | EDNRA (0.63) | EDNRAERAP2CASP1CASP3CASP4 | |
| SCHEMBL30839334 | 0.86 | EDNRA (0.61) | EDNRAERAP2CASP1CASP3CASP4 | |
| SCHEMBL7404432 | 0.86 | EDNRA (0.67) | EDNRACASP1CASP3CASP4CASP5 | |
| SCHEMBL2193290 | 0.86 | EDNRA (0.56) | EDNRAERAP2CASP1CASP3CASP4 | |
| SCHEMBL2193967 | 0.86 | BACE1 (0.51) | EDNRAERAP2CASP1CASP3CASP4 | |
| SCHEMBL1652403 | 0.86 | KDM4E (0.58) | ERAP2CTSCKMT2AL3MBTL1IL1RN | |
| SCHEMBL30533184 | 0.84 | EDNRA (0.76) | EDNRAERAP2KMT2AL3MBTL1MMP2 | |
| SCHEMBL1877671 | 0.84 | ERAP2 (0.64) | EDNRAERAP2CASP1CASP3CASP4 | |
| SCHEMBL1877672 | 0.84 | ERAP2 (0.64) | EDNRAERAP2CASP1CASP3CASP4 | |
| SCHEMBL3187724 | 0.84 | ERAP2 (0.55) | ERAP2CTSCKMT2AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985402-B2 | Ultrasound contrast agent of peptide monomers; peptide vectors having high KDR binding affinity; gas filled microvesicle containing a fluorinated gas and a phospholipid | BRACCO SUISSE SA (CH) | 2011-07-26 | — | — | US | disclosed |
| US-20080152594-A1 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES | BRACCO SUISSE SA (CH) | 2008-06-26 | — | — | US | disclosed |