Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21595955 | 0.87 | NPC1 (0.73) | MTNR1AMTNR1BNPC1ALDH1A1KMT2A | |
| SCHEMBL31483087 | 0.84 | MTNR1A (0.73) | MTNR1AMTNR1BNPC1ALDH1A1NPSR1 | |
| SCHEMBL25268396 | 0.84 | DRD4 (0.57) | MTNR1AMTNR1BNPC1ALDH1A1KMT2A | |
| SCHEMBL3446802 | 0.83 | MTNR1A (0.73) | MTNR1AMTNR1BNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL23539483 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BNPC1ALDH1A1NPSR1 | |
| SCHEMBL5147840 | 0.83 | USP2 (0.67) | MTNR1AMTNR1BNPC1ALDH1A1NPSR1 | |
| SCHEMBL2217897 | 0.82 | NPC1 (0.79) | MTNR1AMTNR1BNPC1ALDH1A1NPSR1 | |
| SCHEMBL3446997 | 0.82 | SMN1; SMN2 (0.55) | MTNR1AMTNR1BNPC1ALDH1A1NPSR1 | |
| SCHEMBL23804030 | 0.82 | DRD4 (0.54) | MTNR1AMTNR1BNPC1ALDH1A1KMT2A | |
| SCHEMBL7094090 | 0.82 | MTNR1A (0.53) | MTNR1AMTNR1BNPC1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019244066-A2 | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2019-12-26 | — | — | WO | disclosed |