Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28734912 | 0.83 | ATM (0.35) | EPHX2ATMTP53 | |
| SCHEMBL28759274 | 0.81 | TP53 (0.51) | ATMTP53 | |
| SCHEMBL29077624 | 0.79 | ATM (0.39) | ATMMEN1KMT2ATP53 | |
| SCHEMBL4728819 | 0.77 | EPHX2 (0.56) | EPHX2TP53 | |
| SCHEMBL29191942 | 0.77 | EPHX2 (0.41) | EPHX2ATMNAMPTHRH3CACNB4 | |
| SCHEMBL28568099 | 0.77 | EPHX2 (0.44) | EPHX2NAMPTFAAHNPY5RCACNB4 | |
| SCHEMBL30884651 | 0.75 | EPHX2 (0.61) | EPHX2NPY5RCYP2C19 | |
| SCHEMBL21938016 | 0.75 | TP53 (0.45) | ATMTP53 | |
| SCHEMBL28011548 | 0.74 | ATM (0.42) | ATMCHRM2MEN1KMT2ATP53 | |
| SCHEMBL22991258 | 0.72 | EPHX2 (0.50) | EPHX2ATMIKBKBCHUKFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810572-B1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIV BARCELONA (ES) | 2023-11-15 | — | — | EP | disclosed |
| CN-112888674-B | Polycyclic compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114340634-A | Heterocyclic compounds as kinase inhibitors | 诺维逊生物股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112888674-A | Polycyclic compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2021-06-01 | — | — | CN | disclosed |
| EP-3810572-A1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | Universitat de Barcelona (ES) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243414-A1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIVERSITAT DE BARCELONA (ES) | 2019-12-26 | — | — | WO | disclosed |