SCHEMBL21596794

SCHEMBL21596794

CCc1ccc(OC)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2noc3ccc(C)cc23)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.37
▸ TP53 P04637 1/20 0.37
▸ BRD4 O60885 3/20 0.36
▸ KAT7 O95251 2/20 0.36
▸ KAT6B Q8WYB5 2/20 0.36
▸ KAT6A Q92794 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ PTGER1 P34995 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.34
▸ KAT5 Q92993 1/20 0.34
▸ KAT8 Q9H7Z6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31605548 1.00 MAPT (0.37) MAPTTP53BRD4KAT7KAT6B
SCHEMBL28514884 0.93 BRD4 (0.38) MAPTTP53BRD4KAT7KAT6B
SCHEMBL29652474 0.93 BRD4 (0.38) MAPTTP53BRD4KAT7KAT6B
SCHEMBL21596783 0.91 KAT7 (0.36) MAPTTP53BRD4KAT7KAT6B
SCHEMBL21596842 0.91 KAT7 (0.36) MAPTTP53BRD4KAT7KAT6B
SCHEMBL21596810 0.91 TSHR (0.39) MAPTTP53BRD4KAT7KAT6B
SCHEMBL30838426 0.91 KAT7 (0.36) MAPTTP53BRD4KAT7KAT6B
SCHEMBL31605563 0.91 KAT7 (0.36) MAPTTP53BRD4KAT7KAT6B
SCHEMBL30838424 0.91 TSHR (0.39) MAPTTP53BRD4KAT7KAT6B
SCHEMBL29652370 0.90 KAT7 (0.41) MAPTTP53BRD4KAT7KAT6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed
EP-3810602-A1 COMPOUNDS CTXT Pty Limited (AU) 2021-04-28 — — EP disclosed
CN-112334466-A Compound (I) CTXT私人有限公司 2021-02-05 — — CN disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 — — US disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 MAPT 1135/4885TP53 3501/4885BRD4 1909/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 MAPT 1136/4885TP53 3504/4885BRD4 1913/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B MAPT 2629/4885TP53 4584/4885BRD4 343/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 MAPT 1136/4885TP53 3504/4885BRD4 1913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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