SCHEMBL21596856

SCHEMBL21596856

COc1ccc(S(=O)(=O)Nc2noc3cc(Br)c(C)cc23)c(OC)c1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 8/20 0.56
KAT7 O95251 7/20 0.56
BRD4 O60885 7/20 0.52
KAT6B Q8WYB5 4/20 0.49
KAT5 Q92993 3/20 0.49
KAT8 Q9H7Z6 3/20 0.49
ALPL P05186 1/20 0.45
ALDH1A1 P00352 2/20 0.43
PKM P14618 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31605606 1.00 KAT6A (0.56) KAT6AKAT7BRD4KAT6BKAT5
SCHEMBL21609249 0.85 KAT6A (0.56) KAT6AKAT7BRD4KAT6BKAT5
SCHEMBL31605550 0.85 KAT6A (0.54) KAT6AKAT7BRD4KAT6BKAT5
SCHEMBL21596843 0.85 KAT6A (0.54) KAT6AKAT7BRD4KAT6BKAT5
SCHEMBL21609150 0.84 KAT6A (0.56) KAT6AKAT7BRD4KAT6BKAT5
SCHEMBL31605558 0.84 KAT6A (0.56) KAT6AKAT7BRD4KAT6BKAT5
SCHEMBL26074265 0.82 KAT6A (0.63) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30545817 0.82 KAT6A (0.63) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21609026 0.81 KAT6A (0.67) KAT6AKAT7BRD4KAT6BKAT5
SCHEMBL21609013 0.78 KAT6A (0.60) KAT6AKAT7BRD4KAT6BKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed
EP-3810602-A1 COMPOUNDS CTXT Pty Limited (AU) 2021-04-28 EP disclosed
CN-112334466-A Compound (I) CTXT私人有限公司 2021-02-05 CN disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 US disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT6A 877/4885KAT7 490/4885BRD4 1909/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT6A 878/4885KAT7 490/4885BRD4 1913/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B KAT6A 160/4885KAT7 271/4885BRD4 343/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 KAT6A 878/4885KAT7 490/4885BRD4 1913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.