SCHEMBL2159690

SCHEMBL2159690

CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)ON1C(=O)CCC1=O)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.43
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TLR2 O60603 1/20 0.36
TLR1 Q15399 1/20 0.36
GLO1 Q04760 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
KMT2A Q03164 2/20 0.33
PLK1 P53350 1/20 0.33
ADORA1 P30542 1/20 0.32
CCKAR P32238 1/20 0.31
CCKBR P32239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1895784 1.00 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL25162403 1.00 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL18379134 1.00 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL61034 1.00 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL20608161 1.00 GLP1R (0.43) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL24486698 0.97 GLP1R (0.41) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL19034919 0.97 GLP1R (0.41) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL3435333 0.94 GLP1R (0.46) GLP1RHPGDHTTSMN1; SMN2TLR2
SCHEMBL30118291 0.94 GLP1R (0.50) GLP1RHPGDHTTSMN1; SMN2BCHE
SCHEMBL29414972 0.93 GLP1R (0.49) GLP1RHPGDHTTSMN1; SMN2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2340049-A1 METHOD OF ACYLATING A PEPTIDE OR PROTEIN Novo Nordisk A/S (DK) 2011-07-06 EP disclosed
WO-2010029159-A1 METHOD OF ACYLATING A PEPTIDE OR PROTEIN NOVO NORDISK A/S (DK) 2010-03-18 WO disclosed