Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 6/20 | 0.35 |
| ▸ | CCKBR | P32239 | 6/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895784 | 0.94 | GLP1R (0.43) | GLP1RGLO1HPGDHTTSMN1; SMN2 | |
| SCHEMBL61034 | 0.94 | GLP1R (0.43) | GLP1RGLO1HPGDHTTSMN1; SMN2 | |
| SCHEMBL18379134 | 0.94 | GLP1R (0.43) | GLP1RGLO1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2159690 | 0.94 | GLP1R (0.43) | GLP1RGLO1HPGDHTTSMN1; SMN2 | |
| SCHEMBL20608161 | 0.94 | GLP1R (0.43) | GLP1RGLO1HPGDHTTSMN1; SMN2 | |
| SCHEMBL25162403 | 0.94 | GLP1R (0.43) | GLP1RGLO1HPGDHTTSMN1; SMN2 | |
| SCHEMBL30118291 | 0.94 | GLP1R (0.50) | GLP1RHPGDHTTSMN1; SMN2CCKAR | |
| SCHEMBL29414972 | 0.92 | GLP1R (0.49) | GLP1RHPGDHTTSMN1; SMN2BCHE | |
| SCHEMBL19034919 | 0.91 | GLP1R (0.41) | GLP1RGLO1HPGDHTTSMN1; SMN2 | |
| SCHEMBL24486698 | 0.91 | GLP1R (0.41) | GLP1RGLO1HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254906-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | Novo Nordisk A/S (DK) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115469-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | NOVO NORDISK A/S (DK) | 2009-09-24 | — | — | WO | disclosed |