Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.63 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.63 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | TNF | P01375 | 1/20 | 0.63 |
| ▸ | IL1B | P01584 | 1/20 | 0.63 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | AXL | P30530 | 6/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30438018 | 1.00 | CRBN (0.63) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL30438142 | 0.97 | CRBN (0.62) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL19436877 | 0.97 | CRBN (0.62) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL22636509 | 0.96 | CRBN (0.61) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL21814682 | 0.96 | CRBN (0.61) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL24142000 | 0.96 | CRBN (0.61) | CRBNIKZF3DDB1IKZF1BRD4 | |
| Hydrochloric Acid SCHEMBL30772822 | 0.96 | CRBN (0.61) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL27347582 | 0.96 | CRBN (0.61) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL19747349 | 0.96 | CRBN (0.61) | CRBNIKZF3DDB1IKZF1BRD4 | |
| SCHEMBL23093113 | 0.94 | CRBN (0.65) | CRBNIKZF3DDB1IKZF1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615779-B | Process for preparing lenalidomide derivatives | 上海科技大学 | 2023-03-24 | — | — | CN | claimed |
| CN-110615779-A | Process for preparing lenalidomide derivatives | 上海科技大学 | 2019-12-27 | — | — | CN | claimed |
| WO-2019242625-A1 | METHOD FOR PREPARING LENALIDOMIDE DERIVATIVES | 上海科技大学 | 2019-12-26 | — | — | WO | claimed |
| WO-2024138128-A2 | CEREBLON DEGRADER CONJUGATES, AND USES THEREOF | GENENTECH, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023193085-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) | 2023-10-12 | — | — | WO | disclosed |
| CN-110615779-B | Process for preparing lenalidomide derivatives | 上海科技大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-110615779-A | Process for preparing lenalidomide derivatives | 上海科技大学 | 2019-12-27 | — | — | CN | disclosed |
| WO-2019242625-A1 | METHOD FOR PREPARING LENALIDOMIDE DERIVATIVES | 上海科技大学 | 2019-12-26 | — | — | WO | disclosed |