SCHEMBL30438142

SCHEMBL30438142

NCCCCNc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.62
▸ IKZF3 Q9UKT9 3/20 0.62
▸ DDB1 Q16531 2/20 0.62
▸ IKZF1 Q13422 2/20 0.62
▸ BRD4 O60885 1/20 0.62
▸ TNF P01375 1/20 0.62
▸ IL1B P01584 1/20 0.62
▸ MAP1LC3B Q9GZQ8 3/20 0.57
▸ AXL P30530 6/20 0.54
▸ STAT3 P40763 1/20 0.53
▸ HDAC3 O15379 1/20 0.51
▸ HDAC1 Q13547 1/20 0.51
▸ CSNK1A1 P48729 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19436877 1.00 CRBN (0.62) CRBNIKZF3DDB1IKZF1BRD4
Hydrochloric Acid SCHEMBL30772822 0.99 CRBN (0.61) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL21814682 0.99 CRBN (0.61) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL22636509 0.99 CRBN (0.61) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL27347582 0.99 CRBN (0.61) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL24142000 0.99 CRBN (0.61) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL19747349 0.99 CRBN (0.61) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL21596986 0.97 CRBN (0.63) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL30438018 0.97 CRBN (0.63) CRBNIKZF3DDB1IKZF1BRD4
SCHEMBL23093113 0.93 CRBN (0.65) CRBNIKZF3DDB1IKZF1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110615779-B Process for preparing lenalidomide derivatives 上海科技大学 2023-03-24 — — CN claimed
WO-2025101912-A1 HELLS HELICASE DEGRADERS AND USES THEREOF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-05-15 — — WO disclosed
CN-109415336-B MDM2 protein degradation agent 密执安大学评议会 2023-08-29 — — CN disclosed
CN-110615779-B Process for preparing lenalidomide derivatives 上海科技大学 2023-03-24 — — CN disclosed
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