Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL27177897 | 0.97 | TP53 (0.61) | TP53GABRR1ALDH1A1TSHROR51E2 | |
| Lactic Acid SCHEMBL1831319 | 0.97 | TP53 (0.61) | TP53GABRR1ALDH1A1TSHROR51E2 | |
| Lactic Acid SCHEMBL22346344 | 0.97 | TP53 (0.61) | TP53GABRR1ALDH1A1TSHROR51E2 | |
| Lactic Acid SCHEMBL8000989 | 0.88 | TP53 (0.50) | TP53GABRR1ALDH1A1TSHROR51E2 | |
| Lactic Acid SCHEMBL8334225 | 0.88 | TP53 (0.50) | TP53GABRR1ALDH1A1TSHROR51E2 | |
| Lactic Acid SCHEMBL31326881 | 0.86 | TP53 (0.69) | TP53GABRR1SLC7A5GSRRNPEP | |
| Lactic Acid SCHEMBL27979213 | 0.86 | TP53 (0.69) | TP53GABRR1SLC7A5GSRRNPEP | |
| Alanine SCHEMBL28814675 | 0.84 | TP53 (0.58) | TP53GABRR1SLC7A5GSRSLC1A3 | |
| Lactic Acid SCHEMBL28814674 | 0.84 | TP53 (0.58) | TP53GABRR1SLC7A5GSRSLC1A3 | |
| Lactic Acid SCHEMBL10934337 | 0.83 | TP53 (0.65) | TP53GABRR1SLC7A5GSRRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649709-B2 | Polymer blends for stimulation of oil and gas wells | Energy Solutions (US) LLC (US) | 2023-05-16 | — | — | US | claimed |
| US-20210207464-A1 | POLYMER BLENDS FOR STIMULATION OF OIL & GAS WELLS | RHODIA OPERATIONS (FR) | 2021-07-08 | — | — | US | claimed |
| US-10982519-B2 | Polymer blends for stimulation of oil and gas wells | RHODIA OPERATIONS (FR) | 2021-04-20 | — | — | US | claimed |
| US-20210095186-A1 | CROSSLINKED PROPPANT-GEL MATRIX | HEXION INC. | 2021-04-01 | — | — | US | claimed |
| US-10883041-B2 | Crosslinked proppant-gel matrix | HEXION INC. (US) | 2021-01-05 | — | — | US | claimed |
| EP-3512918-A1 | POLYMER BLENDS FOR STIMULATION OF OIL&GAS WELLS | Rhodia Operations (FR) | 2019-07-24 | — | — | EP | claimed |
| US-10329478-B2 | Aldehydes as a catalyst for an oxidative breaker | HALLIBURTON ENERGY SERVICES, INC. (US) | 2019-06-25 | — | — | US | claimed |
| US-20180346799-A1 | CROSSLINKED PROPPANT-GEL MATRIX | ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT (CA) | 2018-12-06 | — | — | US | claimed |
| EP-2247687-B1 | COMPOSITIONS AND METHODS OF TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS | BAKER HUGHES A GE CO LLC (US) | 2018-07-25 | — | — | EP | claimed |
| WO-2018052931-A1 | POLYMER BLENDS FOR STIMULATION OF OIL & GAS WELLS | PHODIA OPERATIONS (FR) | 2018-03-22 | — | — | WO | claimed |
| WO-2006010912-A1 | VISCOSIFIED TREATMENT FLUIDS AND ASSOCIATED METHODS OF USE | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| US-20050211435-A1 | Method of forming temporary blocking gel containing guar derivative | BAKER HUGHES, A GE COMPANY, LLC | 2005-09-29 | — | — | US | claimed |
| US-20050077044-A1 | Low residue well treatment fluids and methods of use | BJ SERVICES COMPANY (US) | 2005-04-14 | — | — | US | claimed |
| US-6810959-B1 | MODIFIED POLYSACCHARIDES THAT HAVE HYDROPHILIC (E.G., CATIONIC, ANIONIC, NONIONIC OR AMPHOTERIC) GROUPS, SUCH AS POLYMERIC QUATERNARY AMMONIUM SALT OF HYDROXYETHYL CELLULOSE REACTED WITH A TRIMETHYL AMMONIUM SUBSTITUTED EPOXIDE | BJ SERVICES COMPANY, U.S.A. | 2004-11-02 | — | — | US | claimed |
| US-20040214724-A1 | Compositions and methods for reducing the viscosity of a fluid | HALLIBURTON ENERGY SERVICES, INC. | 2004-10-28 | — | — | US | claimed |
| US-20040048750-A1 | Blending together an aqueous fluid and a hydratable polymer thereby forming a base fluid; wherein the hydratable polymer is a high yielding polymer suitable for forming a crosslinked gel | BJ SERVICES COMPANY | 2004-03-11 | — | — | US | claimed |
| US-6383990-B1 | FRACTURING SUBTERRANEAN FORMATION, BLENDING WATER AND POLYMER SUCH AS CARBOXYLATED GUAR AND TETRAMETHYLAMMONIUM HALIDE. CROSSLINKING TO FORM GEL AND INJECTION INTO FORMATION FOR FRACTURE | BJ SERVICES COMPANY | 2002-05-07 | — | — | US | claimed |
| US-20010007850-A1 | Polymer expansion for oil and gas recovery | BJ SERVICES COMPANY | 2001-07-12 | — | — | US | claimed |
| US-6017855-A | BLENDING TOGETHER AQUEOUS FLUID AND HYDRATABLE POLYMER COMPRISING CARBOXYLATED GUAR TO FORM BASE FLUID; ADDING ZIRCONIUM-BASED AGENT TO FORM CROSSLINKED GEL AND INTRODUCING GEL WITH PRESSURE INTO SUBTERRANEAN FORMATION TO FRACTURE | BJ SERVICES COMPANY (US) | 2000-01-25 | — | — | US | claimed |
| WO-1998054272-A1 | IMPROVED POLYMER EXPANSION FOR OIL AND GAS RECOVERY | BJ SERVICES COMPANY (US) | 1998-12-03 | — | — | WO | claimed |