Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16574793 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL4530231 | 0.84 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL19769248 | 0.82 | MEN1 (0.70) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL10482852 | 0.81 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL10482849 | 0.81 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL875166 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL20299719 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1604188 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6033129 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27889238 | 0.79 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243825-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING, CONJUGATES AND THERAPEUTIC APPLICATIONS | CURADEV PHARMA LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |