Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456690 | 0.94 | KDM4E (0.51) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL966036 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL4214175 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL4210359 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL966479 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL964635 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL4208796 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL4208878 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL966243 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 | |
| SCHEMBL962819 | 0.84 | LMNA (0.54) | LMNAASAH1MAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020004521-A1 | THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, FIBROTIC DISEASES, AND CANCER DISEASES | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2020-01-02 | — | — | WO | disclosed |