Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AIP | O00170 | 1/20 | 0.35 |
| ▸ | SGTA | O43765 | 1/20 | 0.35 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.35 |
| ▸ | STIP1 | P31948 | 1/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603872 | 0.88 | CNR2 (0.45) | ALDH1A1KDM4EMAPTPOLBCNR1 | |
| SCHEMBL21603967 | 0.79 | CNR2 (0.50) | ALDH1A1KDM4EMAPTPOLBCNR1 | |
| SCHEMBL21604012 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTPOLBCNR1 | |
| SCHEMBL21603785 | 0.76 | CYP1A2 (0.45) | ALDH1A1KDM4EMAPTPOLBCNR1 | |
| SCHEMBL21604244 | 0.76 | CNR2 (0.45) | ALDH1A1KDM4EMAPTPOLBCNR1 | |
| SCHEMBL28609323 | 0.76 | CNR2 (0.46) | ALDH1A1KDM4EMAPTCNR1CNR2 | |
| SCHEMBL21603941 | 0.76 | CNR2 (0.46) | ALDH1A1KDM4EMAPTCNR1CNR2 | |
| SCHEMBL21603928 | 0.76 | CNR2 (0.46) | ALDH1A1KDM4EMAPTCNR1CNR2 | |
| SCHEMBL21597867 | 0.75 | CNR2 (0.46) | ALDH1A1KDM4EMAPTPOLBCNR1 | |
| SCHEMBL21597580 | 0.75 | CNR2 (0.46) | ALDH1A1KDM4EMAPTPOLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |