Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332695 | 0.66 | — | — | |
| SCHEMBL23706719 | 0.59 | — | — | |
| SCHEMBL17000125 | 0.58 | — | — | |
| SCHEMBL20014956 | 0.58 | — | — | |
| SCHEMBL9901129 | 0.57 | CD44 (0.32) | DRD2DRD3PNMT | |
| SCHEMBL1970376 | 0.56 | PNMT (0.36) | DRD2DRD3PNMT | |
| SCHEMBL22488571 | 0.55 | — | — | |
| SCHEMBL22908212 | 0.55 | — | — | |
| SCHEMBL7514481 | 0.55 | — | — | |
| SCHEMBL2115873 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019244047-A1 | N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2019-12-26 | — | — | WO | disclosed |