Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21605590 | 0.95 | RORC (0.68) | RORC | |
| SCHEMBL21605618 | 0.92 | RORC (0.61) | RORC | |
| SCHEMBL21605615 | 0.90 | RORC (0.64) | RORC | |
| SCHEMBL29724968 | 0.88 | RORC (0.67) | RORC | |
| SCHEMBL21605521 | 0.88 | RORC (0.67) | RORC | |
| SCHEMBL21605517 | 0.88 | RORC (0.67) | RORC | |
| SCHEMBL21605567 | 0.88 | RORC (0.67) | RORC | |
| SCHEMBL29724917 | 0.88 | RORC (0.67) | RORC | |
| SCHEMBL21605594 | 0.87 | RORC (0.68) | RORC | |
| SCHEMBL21605546 | 0.87 | RORC (0.68) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807261-B1 | PYRIDINYL PYRAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2022-07-13 | — | — | EP | disclosed |
| WO-2019244002-A1 | PYRIDINYL PYRAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |