Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606030 | 0.95 | RORC (0.80) | RORC | |
| SCHEMBL23219323 | 0.95 | RORC (0.80) | RORC | |
| SCHEMBL21606189 | 0.94 | RORC (0.81) | RORC | |
| SCHEMBL21606148 | 0.93 | RORC (0.83) | RORC | |
| SCHEMBL21606156 | 0.92 | RORC (0.81) | RORC | |
| SCHEMBL21606219 | 0.92 | RORC (0.88) | RORC | |
| SCHEMBL23190170 | 0.90 | RORC (1.00) | RORC | |
| SCHEMBL23190002 | 0.90 | RORC (1.00) | RORC | |
| SCHEMBL23189970 | 0.90 | RORC (1.00) | RORC | |
| SCHEMBL21606012 | 0.90 | RORC (1.00) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019244001-A1 | 6-AMINOPYRIDIN-3-YL PYRAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |