Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606993 | 0.77 | MAPT (0.35) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL10052411 | 0.76 | MAPT (0.33) | SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL21606992 | 0.75 | OGA (0.38) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL10076920 | 0.75 | NPC1 (0.33) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL7921134 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL16711669 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL29974039 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL16476934 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL1055102 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL17541632 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN-CILAG S.A. (ES) | 2021-04-29 | — | — | US | disclosed |
| WO-2019243530-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | SMN1; SMN2 103/4885NPC1 1281/4885RAB9A 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.