Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606992 | 0.78 | OGA (0.38) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL21607007 | 0.77 | SMN1; SMN2 (0.36) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL7921134 | 0.69 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL10052411 | 0.68 | MAPT (0.33) | MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14820094 | 0.67 | ALDH1A1 (0.38) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL10076920 | 0.67 | NPC1 (0.33) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL16711669 | 0.66 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL1055102 | 0.66 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL29974039 | 0.66 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL16476934 | 0.66 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2NPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243530-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |