Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532572 | 0.84 | SLC6A4 (0.38) | HTR1ASLC6A2SLC6A3SLC6A4HTR2C | |
| SCHEMBL30396039 | 0.81 | HCRTR2 (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL25145643 | 0.81 | HCRTR2 (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL20412703 | 0.78 | HRH1 (0.47) | HRH1PIM1KCNH2SMN1; SMN2TDO2 | |
| SCHEMBL25290150 | 0.78 | HCRTR2 (0.34) | KCNH2SMN1; SMN2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27157766 | 0.77 | SYK (0.47) | HRH1PIM1KCNH2TIPARPSYK | |
| Hydrochloric Acid SCHEMBL28677440 | 0.77 | HRH1 (0.46) | HRH1KCNH2SMN1; SMN2TDO2HTR1A | |
| SCHEMBL20249279 | 0.76 | CHRNB2 (0.41) | PIM1HTR1ASLC6A2HTR2CROCK1 | |
| Hydrochloric Acid SCHEMBL27157968 | 0.76 | SYK (0.46) | HRH1PIM1KCNH2TIPARPSYK | |
| SCHEMBL13769086 | 0.76 | HRH1 (0.44) | HRH1PIM1KCNH2SMN1; SMN2TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN-CILAG S.A. (ES) | 2021-04-29 | — | — | US | disclosed |
| WO-2019243530-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | HRH1 3096/4885PIM1 3694/4885KCNH2 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.