Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21604547 | 0.70 | OGA (0.52) | ALDH1A1LMNAKDM4E | |
| SCHEMBL31612259 | 0.64 | HRH2 (0.56) | L3MBTL1ALDH1A1HRH3HSD17B10 | |
| SCHEMBL17632140 | 0.63 | SMN1; SMN2 (0.49) | ALDH1A1ADORA2AADORA1PTPN1FBP1 | |
| SCHEMBL3198772 | 0.63 | RAD52 (0.36) | L3MBTL1ALDH1A1ADORA2AADORA1PTPN1 | |
| SCHEMBL11827070 | 0.63 | SMN1; SMN2 (0.50) | L3MBTL1ALDH1A1ADORA2AADORA1HRH3 | |
| SCHEMBL3632268 | 0.63 | SMN1; SMN2 (0.71) | L3MBTL1ALDH1A1HRH3SMN1; SMN2HSD17B10 | |
| SCHEMBL27459046 | 0.63 | FBP1 (0.40) | ALDH1A1FBP1GAASMN1; SMN2 | |
| SCHEMBL27884776 | 0.63 | CYP1A2 (0.33) | — | |
| SCHEMBL21452299 | 0.62 | GNRHR (0.40) | L3MBTL1ALDH1A1HRH3TDP1SMN1; SMN2 | |
| SCHEMBL1033875 | 0.61 | SMN1; SMN2 (0.73) | L3MBTL1ALDH1A1SMN1; SMN2HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243530-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |